I see articles like this: https://www.msn.com/en-us/news/technology/your-immune-system-is-imprinted-with-its-first-coronavirus-exposure/ar-AA16e57s and I get kinda confused. Is it saying that getting an updated vaccine (or recent infection) will somehow c*ckblock the immune system from being able to handle a new strain?
You’ve pretty much got it.
Other seasonal alphacoronaviruses seem to have the same effect for SARS-COV-2, where the immune response is hampered if you’d previously survived an infection from either NL63 or 229E.
There’s no technology at present to overcome imprinting, it’s just a natural phenomenon we’ve known about for decades which regulators ignored when recommending a vaccine series to tens of millions of young people, based on a single spike protein subunit from a strain isolated in Wuhan in 2019, despite the prevalence of new strains with significantly different lineage at the time. You can search the modlog for my previous comment and proximity to the vaccine program.
