74 points

probably important to note that corporations have basically halted research into new antibiotics since the 80s due to high cost

its possible to continue the arms race if a government wanted to

permalink
report
reply

Weirdly it’s unprofitable to create drugs whose ideal case is to never be used and should only be a last resort

permalink
report
parent
reply
27 points

Very excited for phage therapy to mature

permalink
report
parent
reply
26 points

phage therapy

sorry that’s fake communist science, therefore we can’t invest large sums of money into it

permalink
report
parent
reply
24 points

Go Cuba go

permalink
report
parent
reply
18 points
*
Deleted by creator
permalink
report
parent
reply

the very first thing I thought when I learned what a bacteriophage was in the 6th grade I was like “wow that would be an amazing alternative to antibiotics” then “wow I’m a genius I’ll be rich” then I learned the Russians have been doing it for like a hundred years :deeper-sadness:

permalink
report
parent
reply

:xi-plz: but for antibiotics funding

permalink
report
parent
reply

Not to be all :im-vegan: but the continual decline of antibiotics efficacy is way more due to their routine use and misuse in animal agriculture. For every irresponsible doctor or human patient not completing a course, there is an entire farm using them en masse as attempted prophylaxis.

No idea if this specifically has anything to do with that, but every time declining effectiveness of antibiotics comes up I am compelled to mention this

permalink
report
reply
Deleted by creator
permalink
report
parent
reply
24 points
*

The antibiotics also reach water supplies, like when used for shrimp 🦐

That could explain the exposure

permalink
report
parent
reply
17 points
*
Deleted by creator
permalink
report
parent
reply
9 points
*

It’s never that simple. Once you realise plasmids are a thing, bacterial genetics lineages stop being trees and are more like… three-dimensional cobwebs. It only takes adjacency of bacterial colonies for them to spread genetically. (overly simple e.g. respiratory bacterial infection in cow, cow is full of antibiotic resistant other bacteria, bacteria share plasmids, respiratory infection eventually spreads to humans, cow developed AB resistance is now in humans and can spread to most human bacterial species).

“Concept 34 Genes can be moved between species. Genes can be moved between species. Because of the universality of the genetic code, the polymerases of one organism can accurately transcribe a gene from another organism. For example, different species of bacteria obtain antibiotic resistance genes by exchanging small chromosomes called plasmids. In the early 1970s, researchers in California used this type of gene exchange to move a “recombinant” DNA molecule between two different species.”

permalink
report
parent
reply
Deleted by creator
permalink
report
parent
reply

For every irresponsible doctor or human patient not completing a course,

What’s crazy is that completing a course of bacteria or not isn’t even really known if it’s causing the arms race like at all. Like most science, we’re still trying to really pin things down well but there has been some amount of research suggesting it’s not nearly as big a deal as we thought.

permalink
report
parent
reply
8 points

it can be a big deal on an individual level because if you dont get the bacteria thats fucking you up with the first antibiotic it comes back hard and likes to be resistant

i had a resistant infection i needed a 10 day course of iv antibiotics for and it sucked

permalink
report
parent
reply

I was reading some research a year ago that was like, 5-day course of antibiotics are just as effective as 10-day for some bacterial infections (can’t recall the specifics).

permalink
report
parent
reply

Sex-Havers in absolute shambles RN, the Volcel Vanguard marches on :volcel-kamala: :volcel-judge: :volcel-police: :volcel-vanguard:

permalink
report
reply
53 points
*
Deleted by creator
permalink
report
reply

You will have no treats and you will be happy.

permalink
report
parent
reply
18 points
*
Deleted by creator
permalink
report
parent
reply
14 points
*
Deleted by creator
permalink
report
parent
reply
14 points

Well you have to experience love before you catch it

permalink
report
parent
reply
50 points

Fortunately, both cases were successfully cured with potent injections of the antibiotic ceftriaxone

Imagine having to get an injection straight into your peen :ohnoes:

permalink
report
reply

“Can you anesthetize me first?”
“Of course! I’m just going to inject some lidocaine…”
“Great!”
“Straight into…”
“Yeah?”
“Your peen”

permalink
report
parent
reply
16 points

They have to do that for laser hair removal. It’s not so bad.

permalink
report
parent
reply
4 points

You can get laser hair removal for your peen? :thinkin-lenin:

permalink
report
parent
reply

Science

!science@hexbear.net

Create post

Welcome to Hexbear’s science community!

Subscribe to see posts about research and scientific coverage of current events

No distasteful shitposting, pseudoscience, or COVID-19 misinformation.

Community stats

  • 2

    Monthly active users

  • 1.6K

    Posts

  • 37K

    Comments