If you just want them all dead and only care about the resources or the lowly populated land, you would absolutely nuke them. What the rest of the countries gonna do? pout? That’s a big antisemitism right there, you’re gonna face sanctions until the new batch of nuclear warheads is ready.
Aside from the fact that that would be extremely unpopular not only abroad but in Israel, and a definite suicide for Bibi, I am primarily thinking about the radioactive contamination that knows no borders. That’s just a no go. Plus, you know, Israel doesn’t actually have any nukes™ ;)